Chinese invention patent: Protein enrichment detection device based on light-operated fluid transportation and magnetic control sample separation

Inventor: Chongyu Zhu, Yanlei Yu, Yao Lu

Applicant: Fudan University

Patent No.: ZL 202010531798.8

Abstract：

The invention relates to a protein enrichment detection device based on light-operated fluid transportation and magnetic control sample separation. The interior of an optical flow control micro-tube actuator is used for accommodating magnetic nanoparticles, a to-be-detected liquid sample and a detection liquid and is a place for capturing the target protein of magnetic nano particles and reactionbetween the target protein and detection liquid. An electromagnetic control device is arranged in the middle of the exterior of the optical flow control micro-tube actuator, and exertion and cancellation of a magnetic field are achieved by controlling on-off of a power supply; a control light source is arranged above the outer part of the optical flow control micro-tube actuator and is used for driving liquid in the optical flow control micro-tube actuator to finish directional movement; the detection tube is connected with one end of the optical flow control micro-tube actuator, and the optical detection instrument is used for optical detection of liquid in the detection tube. Compared with the prior art, non-contact control can be achieved, portable protein detection can be truly achieved, and meanwhile the risk that a sample is polluted is effectively avoided.